The findings suggest recombinant ADAMTS-13 may be a useful adjunct therapy to plasma exchange among patients who have thrombotic thrombocytopenic purpura (iTTP). Clearance of ADAMTS-13 mediated by ...

There is the Addams Family. And then there is the ADAMTS family. While one is mindless entertainment, the latter may prove to be a new genetic avenue for designing ovarian cancer treatment, scientists ...

An investigational treatment that mimics a key clotting enzyme is effective, safe, and may one day eliminate the need for blood products for people with the rare, life-threatening blood disease ...

Loss of articular cartilage caused by extracellular matrix breakdown is the hallmark of arthritis. Degradative fragments of cartilage oligomeric matrix protein (COMP) have been observed in arthritic ...

The ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family comprises a group of extracellular zinc-dependent endopeptidases that modulate the structure and function of the ...

Cancer specialists at UEA have discovered that several 'ADAMTS' genes are turned off in breast cancer compared to normal breast tissue, while others are switched on. These genes could be targets for ...

Aniara Diagnostica is pleased to announce the availability of 5-ELISA ADAMTS-13 Antigen kit which is a two-site enzyme immunoassay for measuring ADAMTS-13 antigen in plasma or in any biological fluid ...