Patients who experience adverse ocular effects with bisphosphonates have a notably higher risk for osteonecrosis than those who do not experience such events, a large cohort study shows.

Long-term treatment with a bisphosphonate degrades fracture-resistance–toughening mechanisms that contribute to healthy bone, setting the stage for the rare but catastrophic risk of patients ...

Bisphosphonates are a class of drugs that reduce the rate of bone turnover. Osteochemonecrosis is a drug-induced condition in which part of the jawbone dies and cannot regenerate due to lack of blood ...

Please provide your email address to receive an email when new articles are posted on . Despite potential side effects, bisphosphonate therapy may benefit postmenopausal women with osteoporosis by ...

Share on Facebook. Opens in a new tab or window Share on Bluesky. Opens in a new tab or window Share on X. Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window Nonsteroidal ...

Bisphosphonates are widely used in the management of osteoporosis. They are cleared rapidly from the circulation, with about half the administered dose taken up by the skeleton and the rest excreted ...

Osteoporosis is underrecognized and undertreated despite the availability of effective therapies that reduce fracture risks. Bisphosphonates are currently the most widely prescribed pharmacologic ...

Since 2007, there have been several reports suggesting a potential association between the use of bisphosphonates and the occurrence of subtrochanteric or so-called atypical femoral fracture. 1–4 ...

Share on Facebook. Opens in a new tab or window Share on Bluesky. Opens in a new tab or window Share on X. Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window About a year was ...

Adults with moderate to severe chronic kidney disease at high risk for fracture were no more likely to die of any cause when prescribed bisphosphonate therapy compared with adults with CKD who were ...

Bones are living tissues that undergo constant remodelling. In a healthy bone that has finished growing, the breakdown of old bone (by osteoclasts) and the formation of new bone (by osteoblasts) is a ...