The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...
Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...
The contraction of smooth muscle is an essential process underpinning diverse physiological functions ranging from gastrointestinal motility to vascular regulation. At its core, smooth muscle ...
The contractile responses of esophageal smooth muscle (SM) induced by platelet-activating factor (PAF) involve the activation of L-type voltage-dependent calcium channels (L-type VDCCs), ...
New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...
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Compound found in rice bran can suppress intestinal contractions by inhibiting calcium influx
A research team at Toho University has revealed that ferulic acid (FA), a polyphenol abundant in rice bran, suppresses intestinal smooth muscle contractions by inhibiting voltage-dependent calcium ...
The flow of water within a muscle fiber may dictate how quickly muscle can contract, according to a new study. The flow of water within a muscle fiber may dictate how quickly muscle can contract, ...
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