For the first time, researchers have succeeded in developing an artificial DNA base pair that is based on a different ...

The discovery of Hoogsteen base pairs, an alternative pairing mode to the canonical Watson–Crick structure, has significantly broadened our understanding of DNA dynamics. This conformation, in which ...

A team led by Professor Shoichiro Asayama at Tokyo Metropolitan University has synthesized a charge-free molecule designed to sneak plasmid DNA into living cells via hydrogen bonding, dramatically ...

A research team at the University of Cologne has developed an artificial DNA base pair that works according to a new chemical principle. In contrast to natural bases, the novel artificial base pairs ...

Metal-mediated base pairing in nucleic acids represents a transformative approach wherein traditional Watson–Crick hydrogen bonds are replaced or supplemented by coordinate bonds with metal ions. This ...

DNA strands on tiny beads hide and reveal encrypted messages through programmable fluorescence patterns read by flow cytometry.

Getting DNA into a living cell sounds simple, until you remember the cell’s outer membrane acts like a guarded wall. DNA strands carry a negative charge, and they do not cross that wall easily.

Engineers at the University of Pennsylvania and Rice University have refined a technology for editing individual genetic ...

This image illustrates the chemical structures of the five main nucleobases found in DNA and RNA. The pyrimidines, thymine (DNA), uracil (RNA), and cytosine are shown on top while the purines, adenine ...