Inhibitor of apoptosis (IAP) proteins are a family of proteins that are involved in the regulation of various signaling pathways. Although they were initially described to function as endogenous ...

The role of a protein called XIAP in the regulation of cell death has been identified by researchers and has led them to recommend caution when drugs called IAP inhibitors are used to treat cancer ...

Research shows that the IAP-targeting drugs that promote the death of cancer cells also induce the growth and repair of muscle. Few drugs are available to treat muscle injury, muscle wasting and ...

Macrophage and neutrophil apoptotic cell death have been demonstrated to confer resistance to severe tuberculosis (TB) infection in preclinical mouse models of the disease, according to an Australian ...

Agreement covers small molecules targeting the Bcl-2 and IAP apoptosis pathways. American firm Ascenta Therapeutics and Chinese company Ascentage Pharma (APGC) have teamed up to co-develop two of the ...

The role of a protein called XIAP in the regulation of cell death has been identified by Walter and Eliza Hall Institute researchers and has led them to recommend caution when drugs called IAP ...