Tandem mass spectrometry is a powerful tool in proteomics. By ionizing peptides and then fragmenting those ions into smaller product ions, researchers can determine the biomolecules’ amino acid ...

Effective protein characterization depends on the precise isolation and fragmentation of peptide ions within the mass spectrometer, typically coupled with liquid chromatography (LC-MS/MS). In a ...

TOF-SIMS is a mass spectrometry technique in which a solid sample is bombarded by ions, which then release fragments of the surface molecules. The material ejected from the sample typically is from ...

For glycopeptide characterization, mass spectrometry has arisen as the go-to methodology. As well as the instrumental arrangement, a suitable software solution is essential to enable glycopeptide ...

This is the fourth and final article in the series, describing the characterization of protein-based bio-therapeutics by bottom-up analysis at the peptide level (peptide-mapping analysis). This ...

After three years of development, the National Institute of Standards and Technology (NIST) has released a major upgrade of the widely used NIST/EPA/NIH Mass Spectral Library. The library is an ...