Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development, but researchers are unsure how the vast majority of these mutations contribute to cancer because ...

No gene acts alone: interacting variants and protein partnerships can worsen, mask or even rescue disease risk, demanding ...

A new study led by Aaron Hobbs, Ph.D., and Rachel Burge, Ph.D., at MUSC Hollings Cancer Center, reveals why a specific gene ...

Thought LeadersMaxwell Sherman Graduate Student and PhD Candidate Massachusetts Institute of Technology: MIT In this interview, News-Medical speaks to Maxwell Sherman, an MIT graduate student and one ...

CAMBRIDGE, MA -- Cancer cells can have thousands of mutations in their DNA. However, only a handful of those actually drive the progression of cancer; the rest are just along for the ride.

Researchers have developed the first mouse model for a mitochondrial tRNALeu mutation, showing that the associated metabolic disorder results from faulty RNA processing. Studying the role of ...

Researchers have developed a computer model to scan the entire genome of cancer cells to identify driver mutations, which could help researchers find novel drug targets. Cancer is only driven by some ...

A new study published in PLOS Biology suggests that a specific cocktail of dietary supplements may help alleviate behavioral ...

Scientists built a computer model that can rapidly scan the entire genome of cancer cells and identify mutations that occur more frequently than expected, suggesting that they are driving tumor growth ...