By targeting the TRPM4 pathway in solid tumors, scientists may further enhance the necrosis-inducing anticancer therapies available to fight such tumors, he said. "We found that the cancer drug ErSO ...

Immuno–Fluorescence In Situ Hybridization Index Predicts Survival in Patients With Diffuse Large B-Cell Lymphoma Treated With R-CHOP: A GELA Study Clinically annotated microarray data from 425 ...

A distinct signaling pathway called TNF-α drives the transformation of epithelial cells into aggressive tumor cells. During cancer progression, cells activate their own TNF-α program and become ...

Findings show these drugs were linked with a lower risk of progression to inflammatory arthritis compared with tumor necrosis factor inhibitors, although more research is needed to confirm the finding ...

CHAMPAIGN, Ill. — Scientists have identified a protein that plays a pivotal role in the action of several emerging cancer therapies. The researchers say the discovery will likely aid efforts to ...