Mechanistically, thirst starts with the excitation of osmoregulatory cells in a brain structure called the lamina terminalis, which is located in the anterior wall of the third ventricle. The lamina ...

A pharmacist explains treatment options for this rare hormonal disorder Medically reviewed by Erika Prouty, PharmDMedically reviewed by Erika Prouty, PharmD Diabetes insipidus (DI) is a rare disorder ...

Aquaporin-2 (AQP2) is a critical water channel in the renal collecting ducts that governs water reabsorption and urine concentration. Dysregulation of AQP2, through genetic mutations or acquired ...

Central diabetes insipidus is a rare condition that can cause extreme thirst and a frequent need to pee. It occurs when there isn’t enough antidiuretic hormone (ADH) in your body. Diabetes insipidus ...

PHILADELPHIA--(BUSINESS WIRE)--NephroDI Therapeutics, Inc., a biopharmaceutical company developing NDI-5033 for the X-linked/congenital form of Nephrogenic Diabetes Insipidus (NDI), today announced a ...