How does DNA recombination work? It occurs frequently in many different cell types, and it has important implications for genomic integrity, evolution, and human disease. In the alternate pathway ...

An analysis of millions of SARS-CoV-2 genomes finds that recombination of the virus is uncommon, but when it occurs, it is most often in the spike protein region, the area which allows the virus to ...

Researchers have quantified one of the most important and hard-to-measure phenomena in molecular evolution: the effect of genetic recombination on a species' capacity of adaptation. UAB researchers ...

Photoluminescence measuring station: Team member Genghua Yan was responsible for many of the measurements in the study. (Courtesy: Forschungszentrum Jülich/Ralf-Uwe Limbach) The remarkably high ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

Analysis of hundreds of single-cell genomes from Yellowstone National Park shows bacterial species are less cohesive than previously thought.

Scientists at deCODE genetics/Amgen have constructed a complete map of how human DNA is mixed as it is passed down during reproduction. The map marks a major step in the understanding of genetic ...

Spo11-oligo mapping — Upper: the Spo11-oligo map agrees with ssDNA microarray analysis (Buhler et al., PLoS Biology, 2007) but is higher resolution. Lower: Agreement of the Spo11-oligo map with direct ...

“TAR cloning is used to genetically engineer synthetic viruses with novel properties that may be used for the development of new vaccines.” Transformation-associated recombination (TAR) cloning ...