CRISPR-Cas9 is a revolutionary gene-editing tool, but it’s not without its downsides. Now, scientists at Harvard have demonstrated an alternative genetic engineering system called Retron Library ...

While the CRISPR-Cas9 gene editing system has become the poster child for innovation in synthetic biology, it has some major limitations. CRISPR-Cas9 can be programmed to find and cut specific pieces ...

Researchers from the Harvard's Wyss Institute for Biologically Inspired Engineering have created a new gene-editing tool that can enable scientists to perform millions of genetic experiments ...

Retron-based genome editing has been inviting comparisons with CRISPR-based genome editing, especially since researchers have learned that retrons, like CRISPR systems, function as a sort of immune ...

Could a new technique – Retron Library Recombineering – consign CRISPR to the history books? No regular BioTechniques reader will be unfamiliar with both the promise and challenges posed by CRISPR.