Toll-like receptors (TLRs) are members of the pattern recognition receptor (PRR) family. They sense pathogen-derived molecules termed pathogen-associated molecular patterns (PAMPs), as well as ...

The ability of the innate immune system to recognize and eliminate invading microbial pathogens has been largely attributed to Toll-like receptors (TLRs) and TLR-triggered immune response. TLRs, the ...

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At the 2018 Sea Otter Classic, we spent quite a bit of time in the Challenge Tires booth, talking fat tubulars and shedding inner tubes, and inspecting the new bikes of Helen Wyman and Molly Cameron.

Nonemergent target-vessel revascularization (TLR) poses a substantial, independent late mortality risk, even in the era of drug-eluting stents (DES), at least partly because of its risk for subsequent ...

The need for repeat revascularization following PCI in the left main coronary artery is more likely to occur early after the index procedure, but TLR does not appear to be linked to worse survival in ...

The Pirelli P Zero Race TLR is a tyre with pedigree – the previous generation was among the top-rated all-round performance tyres we’ve tested to date. This latest version of the tyre launched in ...

Even in today’s world of smartphones, tablets, and smartwatches, the miniaturization of technology is limited by power demand. No matter how small we can make the circuitry, the batteries still have ...

BERKELEY, CA--Dynavax Technologies Corporation (NASDAQ: DVAX) today announced that it has regained full rights to DV1179, an investigational bifunctional inhibitor of toll-like receptors (TLR) 7 and 9 ...

Weapon lights are a critical component of many law enforcement, and civilian home defense setups. They allow the wielder to positively identify a potential threat, illuminate said threat, and even ...

When searching for the perfect cyclocross tread, sometimes the faithful Challenge Grifo isn’t enough, and a Limus is overkill. That’s where Challenge’s Flandrien tread steps in—splitting the ...

The Pirelli P Zero Race TLR 4S is the Italian brand’s high-performance, all-season tubeless road tyre. Having previously existed only as a (highly rated) clincher tyre, Pirelli finally released an ...