A) Two-photon image of a basal dendrite of L2/3 neuron loaded with Alexa 594. In this example, the spine is ~40 μm below the surface of the slice. Scale bar, 2 μm. (B) Voltage-clamp traces ...
A new study from Pitt researchers challenges a decades-old assumption in neuroscience by showing that the brain uses distinct transmission sites - not a shared site - to achieve different types of ...
They used two-photon imaging to visualize individual axons and synapses in the brain of a live animal. The study was conducted on the APP/PS1 xThy-1GFP-M strain of mice, which is a cross between the ...
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