Alltrna's ML-driven platform optimizes sequence and modifications from natural tRNAs to significantly increase premature termination codon (PTC) readthrough First Alltrna-engineered tRNA ...

There are different kinds of ribonucleic acids that play essential roles in many aspects of molecular biology, including the creation of proteins from gene sequences in DNA. One type of ribonucleic ...

The tRNA3 Leu gene from yeast contains an intervening sequence of 32 nucleotides not present in mature tRNA. This sequence is transcribed and subsequently removed during the maturation of the RNA. To ...

A new advanced, high-throughput sequencing technique should enable scientists to have a firmer grasp on the activity of naturally occurring microbiomes in response to real-world conditions and diet.

Alltrna is advancing a new class of genetic medicines based on the power of tRNA biology to universally treat Stop Codon Disease, which encompasses thousands of genetic diseases caused by a premature ...

The study reports on a newly discovered category of tRNA fragments as well as shows that all tRNAs are rich sources of very diverse short molecules whose characteristics depend on a person's gender, ...

The various identities of cells, whether they are in the brain, heart, kidney, or any other tissue, are defined by the genes they expressed. In basic terms, the genes that are active in a cell are ...

RNAs play an integral part in all kingdoms of life and mediate critical processes from gene regulation to genomic maintenance and protein synthesis. RNAs also have an amazing diversity in structure ...

(PHILADELPHIA) -- Transfer RNAs (tRNAs) are ancient molecules and indispensable components of all living cells - they are found in all three kingdoms of life i.e., in archaea, bacteria and eukaryotes.