Jun 1, 2022 · Cytotoxin is abundant in the cobra venom and undeniably plays a major role in causing local necrotic lesions at the wound site upon snakebite. Cytotoxin exhibits differential cytotoxic …

Dec 1, 2022 · In some African cobras, they comprise more than 70% of the venom proteome. Being less toxic than cobra venom NTXs, CTXs act non-specifically, thereby affecting various tissues and …

Nov 11, 2020 · Venoms of cobras (Naja spp.) contain high abundances of cytotoxins, which contribute to tissue necrosis in cobra envenomation. The tissue-necrotizing activity of cobra cytotoxins, …

Cardiotoxins (cytotoxins, CT) are β-structured proteins isolated from the venom of cobra. They consist of 59–61 amino acid residues, whose antiparallel chains form three ‘fingers’. In contrast to neurotoxins …

Jul 25, 2024 · In a recent study published in Science Translational Medicine, scientists used functional genomics to dissect and understand the cytotoxicity of spitting cobra venom and define the genetic …

Like other elapid venoms, cobra venoms are neurotoxic in nature. However, they also exhibit local cytotoxic effects at the envenomed site, and the extent of cytotoxicity may vary from species to species.

Jul 28, 2023 · Approximate 70% of cobra venom is composed of cytotoxin (CTX), which is responsible for the dermonecrotic symptoms of cobra envenomation.

Cobra venom cytotoxin (CTX) is a non-enzymatic three-finger toxin that constitutes 40–60% of cobra venom. Thus, it plays an important role in the pathophysiology of cobra envenomation, especially in …

Apr 4, 2022 · Cobra venom cytotoxin (CTX) is a non-enzymatic three-finger toxin that constitutes 40-60% of cobra venom. Thus, it plays an important role in the pathophysiology of cobra envenomation, …

Cobra, any of various species of highly venomous snakes, most of which expand the neck ribs to form a hood. Cobras are found from southern Africa through southern Asia to islands of Southeast Asia.