Monoclonal antibody - Wikipedia
A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell lineage made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to …
What are Monoclonal Antibodies and how do they work? - Drugs.com
Jun 3, 2025 · The mAb (ibritumomab) delivers a radioactive substance (Yttrium-90) directly to cancer cells. Another example is Kadcyla, an mAb that is attached to a chemotherapy drug.
Monoclonal Antibodies: Definition & How Treatment Works
Nov 16, 2021 · The generic names of the products often include the letters “mab” at the end of the name. What is the difference between monoclonal antibodies and polyclonal antibodies?
Monoclonal Antibodies and Their Side Effects - American Cancer Society
Bevacizumab (Avastin) is an mAb that targets a protein called VEGF that affects tumor blood vessel growth. It can cause side effects such as high blood pressure, bleeding, poor wound healing, blood …
Monoclonal Antibodies: How They Work, Uses, Side Effects
Apr 19, 2023 · A monoclonal antibody (mAb) is a type of immune protein produced in a lab that binds to a specific protein on a cell called an antigen. As with naturally occurring antibodies, monoclonal …
Monoclonal Antibodies: Uses, Types, Side Effects & COVID-19
Oct 12, 2022 · Minnesota Dept. of Health. "COVID-19 Medications." Oct. 12, 2022. https://www.health.state.mn.us/diseases/coronavirus/meds.html#mab U.S. Food & Drug …
Understanding How Monoclonal Antibodies Work - PubMed
Jun 26, 2023 · The nomenclature of mAbs depends on the origin of each respective mAb. Common suffixes include -omab, -ximab, -zumab, and -umab, representing murine, chimeric, humanized, and …
Monoclonal Antibodies (mAbs) and Proteins: The Biologic Drugs
Aug 12, 2025 · According to the FDA, axalitimab is a humanized mAb used to treat children and adults with chronic graft-versus-host disease (GVHD), a complication that can occur after receiving a bone …
Why mAbs Matter | Quality Matters | U.S. Pharmacopeia Blog
Feb 6, 2025 · What exactly are mAb drugs and how do they work? Read on to learn about monoclonal antibodies and why they’re so important in healthcare. What are antibodies? To understand …
Monoclonal antibodies - World Health Organization (WHO)
Jun 12, 2021 · In recent years, mAb products have dominated the biotherapeutics market, with hundreds of novel mAbs and mAb-like proteins now in clinical development for the treatment of diseases in …