In this introductory review, we will delineate mechanisms of DNA damage and the counteracting repair/tolerance pathways to provide insights into the molecular basis of genotoxicity in cells …

Sep 8, 2023 · There are various types of DNA damage that can happen due to normal cellular processes or exposure to damaging agents in the environment. Several types of DNA damage …

Identify the various types of DNA damage including oxidative damage (e.g., formation of 8-oxo-7,8-dihydroguanine), alkylation, base loss (AP sites), bulky adduct formation, DNA …

There are several types of DNA damage that can occur due either to normal cellular processes or due to the environmental exposure of cells to DNA damaging agents.

DNA damage can occur naturally or via environmental factors, but is distinctly different from mutation, although both are types of error in DNA. DNA damage is an abnormal chemical …

DNA damage is an alteration in the chemical structure of DNA. Common types of DNA damage include DNA base modifications (e.g., base oxidation, deamination, alkylation, etc.), DNA inter- …

Jul 23, 2025 · The four primary types of DNA repair are crucial for preventing the different DNA damage that can occur due to environmental factors like ultraviolet radiation, toxic chemicals, …

Mar 17, 2025 · Cells are continuously faced with endogenous stress (for example, during replication) and exogenous stress (for example, during exposure to ultraviolet radiation) that …

DNA may be modified in a variety of ways, which can ultimately lead to mutations and genomic instability. This could result in the development of a variety of cancers including colon, breast, …

Oct 20, 2023 · Unrepaired DNA damage can lead to genetic mutations that may result in cancer, ageing, and other diseases. Thus, understanding the mechanisms of DNA damage and repair …